Lesson 6: Domain knowledge amplifies agentic benefits

Agentic RAG delivers its strongest gains in domains with structured knowledge and explicit constraints. Healthcare, finance, and legal analysis benefit the most, because they combine retrieval with rule-based reasoning and graph-structured knowledge. Open-domain tasks show more modest gains. The takeaway is that domain modeling is a complementary component of agentic RAG design, not an afterthought: the more structure your domain has, the more an agent can exploit it.